Jansson-Knodell CL, et al. - The researchers carried out a systematic review and meta-analysis to determine sex-based differences in the prevalence of celiac disease in undiagnosed populations. Databases of MEDLINE, Embase, Cochrane and Scopus were searched for screen-detected or undiagnosed celiac disease studies through 2017. The percentage of undetected celiac disease in female and male patients was the primary outcome. Data reported that the pooled prevalence of undetected celiac disease was 0.589% in female participants and 0.415% in male participants. Investigators found that women in undiagnosed populations (identified by general population screening) were at higher risk of celiac disease than men. In screening, diagnosis and management strategies, the increased risk of celiac disease among girls and women should be considered.