Shah SC, et al. - Using the most robust population-based data currently available from Asia-Pacific populations, researchers defined sex-based differences in inflammatory bowel disease (IBD) incidence according to the age of diagnosis. Upon random-effects meta-analysis, they calculated incidence rate ratios of Crohn's disease (CD) and ulcerative colitis (UC) based on age, and compared differences between males and females. The incidence of UC in the age groups between 15 and 65 years ranged from 20% to 42% higher in males compared with females. The data presented in this work indicated a male predominance of both CD and UC for the majority of the age spectrum from adolescence to middle/late-middle age in a pooled analysis of population-based studies from the Asia-Pacific region.