Shah SC, et al. - Using the most robust population-based data currently available from Asia-Pacific populations, researchers identified sex-based differences in the incidence of inflammatory bowel disease (IBD) according to the age of diagnosis. Using random-effects meta-analysis, they calculated Crohn's disease (CD) and ulcerative colitis (UC) incidence rate ratios by age and compared differences between males and females. In the age groups between 15 and 65, the incidence of UC ranged from 20%-42% higher in males compared with females. The data presented in this work showed a male predominance of both CD and UC for the majority of the age spectrum from adolescence to middle/late-middle age in a pooled analysis of population-based studies from the Asia-Pacific region.