Zengin A, Jarjou LM, Janha RE, et al. - Among Gambian adults, the links between cardiac workload, peripheral vascular calcification, and bone parameters were examined herein. A total of 249 females and 239 males aged 40 to 75+ years were recruited in the Gambian Bone and Muscle Aging Study. Researchers found negative links between rate pressure product and areal bone mineral density (aBMD) in females only; following adjustment for appendicular lean mass residuals, aBMD was identified to be lower at the whole body, femoral neck, L ₁ to L ₄ , and radius for every 10% increment in rate pressure product; similar links were evident when adjusted for fat mass residuals. Similar negative links were identified between pulse pressure and aBMD in females only. Experts found consistent links with cardiac parameters and peripheral quantitative computed tomography results at the radius and tibia in females only. Among Gambian women, poorer bone health in relation to multiple markers of cardiac health was reported. A requirement to detect prophylactic strategies to slow/avert the increasing burden in cardiovascular disease and osteoporosis in Sub‐Saharan Africa has been realized in the context of epidemiological transition and changing noncommunicable diseases burden.