Sex‐related differences in patients at high bleeding risk undergoing percutaneous coronary intervention: A patient‐level pooled analysis from 4 postapproval studies
Journal of the American Heart Association Apr 06, 2020
Chandiramani R, Cao D, Claessen BE, et al. - To assess gender‐associated disparities in patients at high bleeding risk (HBR) receiving percutaneous coronary intervention, researchers conducted a patient‐level pooled analysis of 4 postapproval registries. HBR needed fulfillment of at least 1 major or 2 minor criteria of the Academic Research Consortium definition. Major bleeding and major adverse cardiac events (composite of cardiac mortality, myocardial infarction, or definite/probable stent thrombosis) were considered as the outcomes of interest. Women vs men demonstrated higher prevalence of HBR, with considerable disparities in the distribution of criteria. Older age and the presence of more comorbidities was seen in women at HBR, while males at HBR were more commonly smokers, with previous myocardial infarction and more complex coronary lesions. Higher rates of major bleeding but similar major adverse cardiac event rates were reported in women at HBR vs men at HBR at 4 years.
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries