Severity of reduced bone mineral density and risk of fractures in long-term survivors of childhood leukemia and lymphoma undergoing guideline-recommended surveillance for bone health
Cancer Sep 27, 2019
Bloomhardt HM, Sint K, Ross WL, et al. - Researchers studied 542 childhood leukemia/lymphoma survivors attending 2 survivorship clinics to determine the prevalence of reduced bone mineral density (BMD) detected by off-therapy surveillance. In addition, they assessed factors associated with reduced BMD, and the association of reduced BMD with fractures. Post-therapy fractures were reported in 116 cases. They identified 17.2% of survivors with lumbar spine low BMD, and 3.5% of survivors with very low BMD. The highest risk for lumbar spine low BMD was evident among patients who were older at diagnosis, white, and underweight. A greater risk of fractures was observed in correlation with low BMD, highlighting the clinical importance of surveillance.
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries