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Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: A prospective multicentre cohort study (GCEP)

Gut May 14, 2021

Lee JWJ, Zhu F, Srivastava S, et al. - This study was undertaken to explore the incidence of gastric cancer (GC) attributed to gastric intestinal metaplasia (IM), and validate the Operative Link on Gastric Intestinal Metaplasia (OLGIM) for targeted endoscopic surveillance in regions with the low-intermediate incidence of GC. Researchers conducted a prospective, longitudinal, and multicentre study in Singapore including 2,980 patients who had undergone screening gastroscopy with standardized gastric mucosal sampling, from January 2004 and December 2010, with scheduled surveillance endoscopies at year 3 and 5. They imply a risk-stratified method and recommend that high-risk individuals (OLGIM III–IV) have endoscopic surveillance in 2 years, intermediate-risk patients (OLGIM II) in 5 years.

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