Severe or critical hypotension during post cardiac arrest care is associated with factors available on admission - A post hoc analysis of the TTH48 trial
Journal of Critical Care Nov 06, 2020
Hästbacka J, Kirkegaard H, Soreide E, et al. - This study was conducted to evaluate if severe or critical hypotension can be predicted, based on patient and resuscitation characteristics in out-of-hospital cardiac arrest (OHCA) patients. Researchers also investigated the relationship of hypotension with mortality and neurological outcome. They performed a post hoc analysis of the TTH48 study, to randomize 355 out-of-hospital cardiac arrests patients to targeted temperature management treatment at 33 °C for either 24 or 48 h. The results of this study demonstrated that diabetes, non-shockable rhythm, longer delay to ROSC, and lower admission MAP were prognosticators of severe or critical hypotension. It was reported that severe or critical hypotension was correlated with poor outcome.
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