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Severe neonatal hypoglycaemia and intrapartum glycaemic control in pregnancies complicated by type 1, type 2 and gestational diabetes

Diabetic Medicine Oct 16, 2019

Yamamoto JM, et al. - Among women with type 1, type 2 or gestational diabetes, experts aspired to explore whether in-target intrapartum glucose control was correlated with neonatal hypoglycaemia. Multiple logistic regression has been used to investigate the link between maternal intrapartum glycaemic control and neonatal hypoglycaemia, adjusting for covariates. Among 157, 267 and 3,256 women with type 1, type 2, and gestational diabetes, intrapartum glucose testing was available. After adjustment for neonatal factors (large for gestational age, preterm delivery and infant gender), no significant connection was found between in-target glycaemic control and neonatal hypoglycaemia in this large retrospective cohort study. Neonatal hypoglycaemia has been significantly linked to risk factors present prior to the intrapartum period like a large-for-gestational-age infant and glycaemic control. Future trials must explore whether more relaxed intrapartum glycaemic targets can be safer and produce comparable neonatal outcomes given the high risk of maternal hypoglycaemia and the resources needed.
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