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Serum vitamin A, zinc and visual function in children with moderate to severe persistent asthma

Journal of Asthma Dec 15, 2018

Andino D, et al. - In this study performed among urban children with and without asthma, researchers determined the prevalence of vitamin A as well as zinc deficiency in conjunction with visual function via a cross-sectional case–control assessment and Snellen visual acuity and Peli Robson contrast sensitivity assessment. Only well-controlled pediatric asthmatic patients between the ages of 8–18 with corrected vision of at least 20/25 in each eye and chronic users of a combination beta agonist-steroid inhaler were included. Overall, 24 patients were enrolled, asthmatic and control groups were matched with respect to body mass index and age. Findings revealed reduced levels of vitamin A and zinc in children with chronic asthma, this was suggested to be possibly associated with disease pathobiology, however, no evidence of frank zinc or vitamin A deficiency was found. In the asthmatic group, reduced contrast sensitivity was observed, which appeared to be not associated with serum vitamin A and/or zinc levels.
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