Fukui Y, Nakamura K, Hirabayashi M, et al. - Researchers sought to examine the potential role of vasohibin‐1 (VASH‐1) in systemic sclerosis (SSc) by assessing the clinical correlation of serum VASH‐1 levels and the expression of VASH‐1 in SSc‐involved skin. Serum VASH‐1 levels were higher in SSc patients, particularly those with diffuse cutaneous involvement, than in healthy controls and positively associated with skin score. In addition, SSc patients with interstitial lung disease had substantially higher serum VASH‐1 levels than those without. According to findings, VASH‐1 upregulation in the skin and sera is associated with dermal and pulmonary fibrotic changes in SSc, whereas the contribution of VASH‐1 to SSc vasculopathy appears to be limited.