Bombelli M, et al. - Researchers studied the association between serum uric acid (SUA) and resistance to antihypertensive drugs in a randomized, double-blind, multicenter trial, the European Lacidipine Study on Atherosclerosis (ELSA). In this trial, the progression of carotid atherosclerosis was compared between patients with moderate hypertension who were treated with either lacidipine or atenolol for 4 years. At randomization and at the termination of the study, evaluations for SUA were carried out. At each titration visit and every 6 months thereafter, measurements for office blood pressure (BP) were analyzed. Ambulatory BP was assessed at randomization and every year thereafter. Findings revealed that the responsiveness to antihypertensive treatment was not influenced by SUA levels in the ELSA study.