O'Reilly MW, et al. - Researchers conducted this retrospective cohort study in a UK primary care database to investigate the sex-specific link between circulating androgens and risk of type 2 diabetes mellitus (T2DM). Study participants included men and women with available serum testosterone and sex hormone-binding globulin results. The researchers observed sexually dimorphic associations of serum testosterone with the risk of incident T2DM. They argued that androgen deficiency and excess should be considered as important risk factors for diabetes in men and women.