Egron C, et al. - Researchers conducted a prospective, observational, and analytical study at Clermont-Ferrand University Hospital to assess the relationship between serum soluble receptor for advanced glycation end-products (sRAGE) and clinical severity of bronchiolitis in hospitalized infants aged <1 year. For this investigation, they examined associations between serum sRAGE and Wainwright score, short-term morbidity attributable to bronchiolitis, causal viruses and risk for recurrent wheezing at 1 year by analyzing data of 93 infants. Data reported that sRAGE levels were significantly lower in acute bronchiolitis patients than in controls but not correlated with disease severity. They found no correlation between serum sRAGE and severity score, respiratory viruses, and recurrent wheezing at 1 year. It was noted that serum sRAGE levels were negatively correlated with age.