Napoli N, et al. - In this cross-sectional study, the researchers assessed serum sclerostin and bone turnover markers in latent autoimmune diabetes in adults (LADA) compared with those in type 2 diabetes (T2D) as well as whether metabolic syndrome (MetS) affects sclerostin in T2D or LADA. They enrolled 98 subjects with T2D and 89 with LADA from the Action LADA and Non Insulin Requiring Autoimmune Diabetes cohorts. Nondiabetic participants were used as controls. Findings revealed that bone resorption was decreased in patients with T2D and LADA compared with nondiabetic controls. On the other hand, circulating sclerostin was increased in patients with T2D only.