Yıldız M, et al. - In this investigation, researchers sought to examine the serum renin levels of patients (n = 24) , 14 women (mean age:42.35 ± 9.53) and 10 men (mean age:43.8 ± 6.87), with idiopathic sudden sensorineural hearing loss (ISSNHL) and asymptomatic healthy volunteers (n = 24), 14 women (mean age:42.4 ± 4.7) and 10 men (mean age:41.4 ± 4.59). Individuals underwent pure-tone audiometry and serum renin levels have been measured. Data reported that serum renin levels of the patients and controls were 788.01 ± 327.8 and 282.37 ± 107.73 pg/mL, respectively. According to findings, serum renin levels in patients with ISSNHL were higher than controls. A statistically significant strong positive association was found between serum renin level and the severity of hearing loss.