Gao J, Song Y, Wang D, et al. - Given a lack of effective evaluation methods for the risk of abortion in polycystic ovary syndrome (PCOS) patients, researchers herein investigated PCOS patients for their serum levels of platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and soluble fms-like tyrosine kinase-1 (sFlt-1) and evaluated the predictive values of these measured for the pregnancy outcomes in the PCOS patients.

• PCOS patients with abortion exhibited abnormal levels of serum PDGF, EGF, and sFlt-1 and these levels were noted to be closely linked with the pregnancy outcome in these patients.

• Combination of the three levels showed the highest predictive value for the pregnancy outcome of PCOS patients.

• Following were the independent factors influencing the pregnancy outcome of PCOS patients: age, BMI, diabetes, hypertension, endometrial thickness, and serum PDGF, EGF, and sFlt-1 levels.