Liu Q, et al. - In this investigation involving 51 patients (aged 6 to 42 years), researchers examined the role of advanced oxidation protein products (AOPPs) in the pathogenesis of Henoch–Schonlein purpura (HSP), a type of leukocytoclastic vasculitis. According to results, serum levels of AOPPs in HSP patients and the HSP severity scores were positively correlated, implying that AOPPs could be used as one of the indicators for disease severity and prognosis during the course of the disease. In addition, it gives a theoretical basis for vitamin C, vitamin E, and other antioxidants to be used in the treatment of HSP. Overall, the authors concluded that AOPPs have an important role to play in HSP pathogenesis, particularly in patients of the renal type.