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Serum high-sensitivity C-reactive protein, tumor necrosis factor-α, interleukin (IL)-1β, IL-17A and IL-23 levels in patients with hidradenitis suppurativa

Cytokine May 30, 2021

Öztürk GS, Ergun T, Eyüboğlu İP, et al. - In the present study, the researchers sought to evaluate the serum levels of proinflammatory cytokines TNF-α, IL-1β, IL-17A, IL-23 and high-sensitivity C-reactive protein (hs-CRP) in patients with hidradenitis suppurativa (HS), chronic, recurrent inflammatory skin disease that leads to scar formation, and to assess the influence of treatment on cytokine levels. Serum proinflammatory cytokine and hs-CRP levels were measured in 24 healthy controls and 26 HS patients at baseline and 3 months later using enzyme-linked immunosorbent assay kits. There is insufficient evidence to recommend TNF-α, IL-1β, IL-17A or IL-23 as serum biomarkers in HS. hs-CRP can be used to assess treatment efficacy and systemic inflammation.

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