Kordulewska NK, Kostyra E, Piskorz-Ogórek K, et al. - Since individuals with autism often show dysfunction of cytokines, researchers assessed the utility of these to serve as an aid to clinicians for diagnosis of Autism Spectrum Disorder (ASD). This study included 42 patients with ASD and 20 matched controls. A significantly higher level of IL-1β, IL-4, IL-6 and IL-13 was detected in individuals with autism vs controls. The presence of an interactive network between cytokines was suggested by the observed significant correlations between the levels of cytokines. In ROC analysis, the 4-factors (IL-1β, IL-4, IL-6 and IL-13) were suggested to be the potential biomarkers in ASD diagnosis. Among children with ASD, varied serum levels of cytokine were observed. In this study, the likelihood of using an appropriate selection of serum cytokine for the diagnosis of ASD was supported and the necessity to standardize quantitative methods for serum analysis was highlighted.