Darweesh SK, et al. - Researchers evaluated serum cytokeratin-18 (CK18) in nonalcoholic fatty liver disease (NAFLD) and hepatitis C virus (HCV) fibrosis/steatosis. Further, they correlated its performance with the diagnostic accuracy of transient elastography (TE) and controlled attenuation parameter (CAP) in the diagnosis of fibrosis/steatosis in these patients. They performed TE/CAP and labs including serum CK18 in 3 equal groups of participants (n=135): group I included patients with chronic HCV, group II included NAFLD patients, and group III included control participants. Outcomes revealed strong correlation of serum CK18 to the development/progression of NAFLD and HCV-related fibrosis/steatosis. They noted a high correlation between TE and liver biopsy results. The diagnostic yield of CK18 and other noninvasive modalities increases by combining these tests.