Kaneko R, et al. - This study encompassed an analysis of the biochemical markers for detecting early-stage atherosclerosis in individuals with type 2 diabetes mellitus (T2DM). A strong and independent connection was discovered between cystatin C with arterial wall elasticity in T2DM patients without apparent arterial wall thickening. This, in turn, depicted the degree of subclinical atherosclerosis. Hence, cystatin C was revealed to be a potentially useful marker of early-stage atherosclerosis.