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Serum CD64 and ascitic fluid calprotectin and microRNA-155 as potential biomarkers of spontaneous bacterial peritonitis

European Journal of Gastroenterology & Hepatology Jul 16, 2019

Nabiel Y, et al. - In this observational comparative study involving 103 patients with ascites, researchers assessed CD64, calprotectin, and microRNA-155 (miR-155) levels as diagnostic markers of spontaneous bacterial peritonitis (SBP) and the impact of using more than one use on the same spot over their diagnostic efficiency. Study participants admitted to the Tropical Medicine Department, Mansoura University Hospital, Egypt, divided into 2 groups: case group (64 patients) with ascites with SBP and control group (39 patients) with decompensated cirrhotic non-SBP ascites. Investigators found that CD64, calprotectin, and miR-155 were good SBP diagnostic markers and greater diagnostic efficiency was achieved by using this combination.
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