Xu SL, et al. - In this meta-analysis of 8 studies with 739 cases, researchers examined the link between serum cardiac troponin (cTn) and mortality in pulmonary hypertension (PH) patients. Studies inception to October 25, 2017 were identified from PubMed and EMBASE and were stratified according to type of troponin (cTnT vs cTnI), region (Europe vs America), and follow-up length (≤3 years vs >3 years). The range of cTn elevation was from 14.3% to 94.5%. Findings revealed that, in patients with elevated cTn vs patients with normal cTn levels, death was reported in 48.8% (39/80) vs 18.6% (45/242), respectively. In PH patients, cTn elevation was found to be significantly associated with an increased mortality risk. Compared to cTnT, cTnI allowed a better mortality prediction. Additionally, increased mortality was observed in American populations vs European populations. This finding was independent of the follow-up length of the studies.