Wang C, et al. - Because serum albumin is known for its neuroprotective effects and is a marker of improved acute ischemic stroke (AIS) patient outcomes, researchers intended to determine if there is an association between serum albumin and hemorrhagic transformation (HT), a major complication of AIS, by performing multivariate logistic regression analysis. From 2012 to 2016, they prospectively and consecutively enrolled AIS patients admitted to the Department of Neurology of West China Hospital. They recruited a total of 1,996 AIS patients, 135 of whom developed HT. With higher serum albumin tertile, the risk of HT decreased stepwise. In AIS patients younger than 60 years, higher serum albumin was related to lower HT risk in a dose-dependent manner.