Havers FP, Reed C, Lim T, et al. - This study was undertaken to investigate the prevalence of SARS-CoV-2 antibodies in convenience samples from several geographic sites in the US. Researchers conducted a cross-sectional study performing serologic testing on a convenience sample of residual sera obtained from persons of all ages. They collected serum from March 23 through May 12, 2020, for routine clinical testing by 2 commercial laboratory companies. They investigated serum samples from 16,025 persons, 8,853 (55.2%) of whom were women; 1205 (7.5%) were 18 years or younger and 5845 (36.2%) were 65 years or older. Most persons in 10 diverse geographic sites in the US had not been infected with SARS-CoV-2 virus from March to early May 2020. According to the findings, the estimated number of infections, nevertheless, was much greater than the number of reported cases in all sites. The data may reflect the number of individuals who had mild or no illness or who did not seek medical care or undergo testing but who still may have contributed to ongoing virus transmission in the population.