Rikken JFW, Kowalik CR, Emanuel MH, et al. - Researchers conducted an international, multicenter, open-label, randomized controlled trial in 10 centers in the Netherlands, UK, USA and Iran between October 2010 and September 2018 in order to determine if septum resection improves reproductive outcomes in women with a septate uterus. Eighty women with a septate uterus were randomly assigned to septum resection (n = 40) or expectant management (n = 40). Outcomes suggest that reproductive outcomes in women with a septate uterus did not improve by hysteroscopic septum resection.