Honda K, et al. - In this prospective study involving 18 patients with previously untreated cN0 tongue cancer, researchers evaluated the utility of a novel sentinel lymph node biopsy technique utilizing preoperative computed tomographic (CT) lymphography followed by the intraoperative indocyanine green fluorescence method. In patients with cN0 tongue cancer, the novel sentinel lymph node biopsy technique of preoperative CT lymphography mapping with intraoperative indocyanine green fluorescence has a strong ability to identify sentinel lymph nodes. Since the intraoperative indocyanine green method alone is unable to identify sentinel lymph nodes in the neck region, this combined method has clinical potential as a sentinel lymph node biopsy technique that does not need radioisotopes.