He YT, et al. - In this pilot study, researchers studied the specificity and predictive value of mucosal brush biopsy (MBB) from the oral cavity, a new diagnostic test for peanut allergy. They performed oral MBB and serum testing for peanut sIgE on 20 individuals with no history of adverse reactions from eating peanuts and compared the data with previously published data from 10 individuals with a history of clinical peanut allergy. Findings revealed oral MBB as highly sensitive and specific for screening individuals with and without oral cavity clinical reactivity to peanuts. For oral MBB and sIgE testing, the optimal cutoff levels were 0.12 kU/L and 1.0 kU/L, respectively.