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Sensitivity and specificity of serum and synovial fluid markers in diagnosis of infection in head-neck taper corrosion of metal-on-polyethylene total hip arthroplasty

Journal of Arthroplasty Jul 15, 2020

Kwon YM, Mahajan J, Tirumala V, et al. - In this study, the usefulness of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and synovial fluid markers was examined in diagnosing PJI in failed metal-on-polyethylene (MoP) total hip arthroplasty (THA) due to head-neck taper corrosion. Researchers examined a sum of 89 consecutive individuals with MoP THA with head-neck taper corrosion in 2 groups: infection group (n = 11) and non-infection group (n = 78). They further examined serum cobalt and chromium levels. The outcomes of this research imply that ESR and CRP are beneficial in excluding PJI, whereas both synovial white blood cell count and neutrophil percentage in hip aspirate are beneficial markers for diagnosing infection in MoP THA patients with head-neck taper corrosion correlated adverse local tissue reaction.

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