Hjerpsted JB, et al. - The effects of semaglutide on fasting and postprandial glucose and lipid responses, and on gastric emptying were investigated in this study. In subjects with obesity, semaglutide improved fasting and postprandial glucose and lipid metabolism. Overall gastric emptying was similar to placebo. However, the observed first-hour delay with semaglutide could add to a slower entry of glucose into the circulation.