Kitahata R, et al. - Subjective (self-rated), family-rated, and objective (researcher-rated) cognitive functions were evaluated in patients with breast cancer after chemotherapy. This prospective study concluded that in patients with breast cancer, impairments in subjective cognition could be transient after chemotherapy. Moreover, patients and their families, on their cognitive functions, appeared to share similar prospects.

• A prospective study was performed to trace self-rated cognitive functions in 30 patients with breast cancer at the completion of chemotherapy (T0) and 6 months later (T1).
• The authors evaluated subjective cognitive functions with Cognitive Failures Questionnaire (CFQ), Dysexecutive Questionnaire (DEX-S), and Everyday Memory Checklist (EMC-S) for attention, executive function, and episodic memory, respectively.
• For this study, their family members also completed DEX-I and EMC-I for executive function and episodic memory, respectively.
• Furthermore, they investigated objective cognitive functions.
• They compared self-rated cognitive functions with the normative data and these were compared between T0 and T1.
• Correlation coefficients were calculated between self-rated and other cognitive functions.

• While no participant had abnormal CFQ scores , 6 (20.0%) and 2 (6.7%) participants demonstrated higher DEX-S and EMC-S scores than the normative data, respectively, at T0.
• DEX-S and EMC-S scores were normalized in 3 (50.0%) and 2 (100.0%) participants, respectively, at T1.
• There were no participant who indicated increases in CFQ scores.
• The authors found no changes in objective cognitive functions from T0 to T1.
• At both T0 and T1, DEX-S and DEX-I or EMC-S and EMC-I scores were correlated, which did not survive multiple corrections.
• No association was observed between subjective and objective cognitive functions.