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Secretin improves visualization of nondilated pancreatic ducts in children undergoing mrcp

American Journal of Roentgenology Feb 10, 2020

Li Y, Dillman JR, Anton CG, et al. - Experts intended to evaluate whether secretin improves visualization of a nondilated pancreatic duct and whether it improves identification of variant duct anatomy on MRCP in pediatric individuals. They designed a retrospective review of MRCP images that were prospectively obtained of 50 volunteers without a history of the pancreatic disease who ranged in age from 6 to 15 years old. The results showed that the frequency of image quality scores of 4 or greater allocated to 3D MRCP images was statistically significantly greater after secretin administration for reviewer 2 and reviewer 3 and approached statistical significance for reviewer 1. In a cohort of children with nondilated pancreatic ducts, secretin administration increased subjective MRCP image quality, improved subjective visualization of the pancreatic duct, and gave greater sensitivity for anatomic variants such as pancreas divisum.
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