Lallas A, Apalla Z, Kyrgidis A, et al. - In this prospective cohort study, researchers quantified the risk and examined the time of occurrence of second primary melanoma (SPM). In addition, they identified risk factors for SPM and evaluated the usefulness of total body photography (TBP) and digital dermatoscopic documentation (DDD) for SPM detection. The study sample consisted of patients with recently diagnosed melanoma who underwent sequential clinical and dermatoscopic examinations for up to 5 years. According to findings, 46 of 977 patients developed SPM. Investigators found that patients with melanoma had an 8% risk of developing an SPM within 5 years. TBP and DDD contributed significantly to the early detection of SPM. Potent predictors of SPM were high nevus count, fair phototype, and occupational sun exposure.