Sarcopenia is a prognostic factor for overall survival in elderly patients with head-and-neck cancer
European Archives of Oto-Rhino-Laryngology Mar 07, 2019
Chargi N, et al. - Researchers assessed 85 elderly patients with head-and-neck squamous cell carcinoma (HNSCC) treated between 2015 and 2018 to investigate the relationship between skeletal muscle mass (SMM), muscle function (MF), sarcopenia (SMM and MF combined), and overall survival (OS). They observed the worst median OS in those treated with curative intent with sarcopenia (12.07 months) in comparison to cases without sarcopenia (13.60 months). They noted that SMM and MF separately were not significant predictors of OS. Sarcopenia is related to impaired OS in these patients, and sarcopenia was deemed a superior predictor of OS vs low SMM or low MF separately.
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