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Sarcopenia, a strong determinant for prolonged feeding tube dependency after chemoradiotherapy for head and neck cancer

Head & Neck Sep 06, 2019

Karsten RT, Al-Mamgani A, Bril SI, et al. - In this regression analyses, researchers explored the connection between skeletal muscle mass index (SMI), as a measure of sarcopenia, and prolonged (> 90 days) feeding tube dependency in 128 patients with head and neck cancer (HNC) treated with primary chemoradiotherapy (CRT). Investigators found that 61 patients became prolonged feeding tube-dependent. In patients with HNC treated with primary CRT, sarcopenia, as measured by SMI at C3 level on routine CT imaging of the head and neck area, contributes to the risk of prolonged feeding tube dependency. Before treatment, as sarcopenia may be a modifiable factor, it should be explored as a target for pretreatment patients' condition.
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