Sharbel DD, et al. - In this population-based analysis involving 198 patients with salivary clear cell carcinoma, researchers described predictive clinicopathologic factors and treatment outcomes. From 1982 to 2014, the Surveillance, Epidemiology, and End Results database were queried. To determine disease-specific survival (DSS) and predictive clinicopathologic factors, Multivariate Cox and Kaplan-Meier analyses were performed. Data reported that overall incidence was 0.011 per 100,000 people, with no significant annual percentage change across years. It was noted that 5-, 10-, and 20-year DSS rates were 81.3%, 69.6%, and 55.3%, respectively. Compared with treatment with combination radiation and surgery or radiation monotherapy, treatment with surgery alone had better 10-year DSS. Findings suggested that salivary clear cell carcinoma has a good overall prognosis. Localized disease patients and surgically treated patients have more favorable prognoses. There is a poorer prognosis for male patients and those with regional or distant metastatic disease at presentation.