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Safety of non-insulin glucose-lowering drugs in pregnant women with pre-gestational diabetes: A cohort study

Diabetes, Obesity and Metabolism Jun 13, 2018

Cea-Soriano L, et al. - Researchers explored the link between use of non-insulin antidiabetics in early pregnancy and the risk of miscarriages, stillbirths and major structural malformations. Using electronic medical records from The Health Improvement Network (THIN), a cohort of 1511 pregnant women with pre-gestational diabetes linked to live births were identified for the period 1995 to 2012. It was observed in the findings that use of non-insulin antidiabetics early in pregnancy was not correlated with greater risks of foetal losses or major malformations than was insulin among women with diabetes.
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