Klautz RJM, et al. - This study aimed to assess the safety, effectiveness and haemodynamic performance of a new bovine stented aortic valve bioprosthesis (Avalus). Findings revealed a good safety profile and clinical effectiveness of the Avalus valve except for bleeding rates. The linearized rates of all and major haemorrhage seemed related to long-term anticoagulation for non-valvular indications and the length of follow-up of this cohort.