Komoto S, et al. - A post hoc analysis of data from a large, prospective, observational study was conducted to determine the safety and efficacy of leukocytapheresis (LCAP) in elderly patients with ulcerative colitis (UC). This investigation was conducted at 116 medical facilities in Japan between May 2010 and December 2012. Out of eight hundred forty-seven patients involved in this study, LCAP was used in 75 (8.9%) elderly patients (≥ 65 years) and 772 (91.1%) non-elderly patients. Real-world data showed that the safety and tolerability of LCAP were comparable in the elderly and non-elderly groups, indicating that it was well tolerated by elderly UC patients.