Routine endometrial receptivity array in first embryo transfer cycles does not improve live birth rate
Fertility and Sterility Jan 20, 2021
Riestenberg C, Kroener L, Quinn M, et al. - Patients who undergo personalized embryo transfer (pET) after endometrial receptivity array (ERA) vs frozen embryo transfer (FET) with standard timing in first single euploid FET cycles were compared with respect to the live birth rate. In addition, the rate of displacement of the window of implantation was reported in an infertile population without a history of implantation failure. Researchers conducted this prospective cohort study including a total of 228 single euploid FET cycles in the analysis. These comprised 147 (64.5%) ERA/pET cycles, and 81 (35.5%) standard timing FET cycles. No differences in the live birth rate were noted between patients who underwent FET with standard timing and patients who underwent ERA/pET, 45/81 (56.6%) and 83/147 (56.5%), respectively. Based on findings, the routine use of ERA is not supported in an unselected patient population undergoing first autologous single euploid programmed embryo transfer.
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