Role of the histone deacetylase inhibitor valproic acid in high-fat diet-induced hypertension via inhibition of Histone deacetylase (HDAC) 1/angiotensin II axis
International Journal of Obesity Aug 29, 2017
Choi1 J, et al. – Researchers tried to find out the mechanism of valproic acid–induced prevention of hypertension. It was considered that valproic acid (VPA) prevented high–fat diet (HFD)–induced hypertension by downregulating angiotensin II and its receptor via inhibition of Histone deacetylase (HDAC) 1, offering a novel therapeutic option for HFD–induced hypertension.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty -
Paid Market Research Surveys -
Case discussions, News & Journals' summaries
