Maschio M, Mengarelli A, Zarabla A, et al. – Via performing a retrospective study, researchers assessed the effectiveness of pregabalin (PGB) in the treatment of polyneuropathy (PN) in multiple myeloma patients. Medical charts were reviewed for 108 consecutive patients with PN myeloma. Upon neurophysiological evaluation, patients exhibited a significant reduction in sensory nerve action potential amplitude, conduction velocity, and distal latency of sensory nerves between the first and the last neurological examination. Improvement in neurological symptoms during PGB therapy was noted in the total population, despite the presence of a distal, sensory axonal neuropathy, as demonstrated by neurophysiological examination.