Berry N, et al. - In this prospective observational study, the researchers intended to evaluate and correlate ulcerative colitis (UC) disease activity by clinical criteria, endoscopy, histology, serum and fecal biomarkers, and 18-Fluorodeoxyglucose positron emission tomography-computerized tomography (FDG PET-CT). They enrolled 60 eligible patients of UC into three groups (26 remission, 24 moderate and 10 severe activity) as per Mayo score and FDG PET-CT was performed within 72 h of colonoscopy. Results of this study suggested that FDG PET-CT is a reliable noninvasive tool for detection of disease activity, the extent in UC with good correlation with Mayo score, histology and fecal biomarkers and accurate predictor of disease remission.