Albokhary K, Aljaser F, Abudawood M, et al. - Researchers conducted this cross-sectional study to assess the status of antioxidant enzymes -superoxide dismutase (SOD) and catalase (CAT) with different stages of diabetic retinopathy (DR) severity in patients with type 1 and type 2 DM. Participants in the study were 148 patients with type 1 DM (n=17); type 2 DM (n = 96) and non-diabetes controls (n = 35). In patients with diabetes, both SOD and CAT levels were lower than in non-diabetic controls. A significant positive association has been found between HbA1C level and severity of DR. Oxidative stress and reduced antioxidant defenses are correlated with DR progression to its proliferative DR stage.