Chan HC, Chan HC, Liang CJ, et al. - In this study, the role of LDL composition was evaluated in promoting early vascular aging in SLE patients. Researchers chromatographically divided plasma LDL from 45 SLE patients (SLE‐LDL) and from 37 normal healthy controls (N‐LDL) into 5 subfractions (L1–L5), and the subfraction composition was examined. They evaluated associations between subfraction levels and signs of early vascular aging. The data exhibit that in SLE patients, an increase in plasma L5 levels, not total LDL concentration, may promote early vascular aging, leading to premature atherosclerosis.