Ribolsi M, et al. - Researchers examined the role of high-resolution manometry (HRM) findings, presence of gastroesophageal reflux disease (GERD), and proton-pump inhibitor (PPI) therapy on dysphagia perception in dysphagic patients. For this investigation, 37 nonerosive reflux disease (NERD) patients with only dysphagia (group 1) and 52 patients with both dysphagia and typical GERD symptoms (group 2) were evaluated with symptom scores, HRM combined with impedance and 24 hours impedance-pH monitoring. According to the findings obtained, 40% of dysphagic patients showed a pathologic acid exposure time (AET) and reduced peristaltic vigor. An adequate PPI therapy significantly reduces dysphagia frequency and severity and improves the esophageal peristaltic force in these patients.