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Role of anti-Müllerian hormone and testosterone in follicular growth: A cross-sectional study

BMC Endocrine Disorders Jul 13, 2020

Lv PP, Jin M, Rao JP, et al. - In this retrospective cross-sectional survey, researchers used diminished ovarian reserve (DOR) and polycystic ovarian syndrome (PCOS) as two extremes of ovarian reserve (deficient and excessive respectively) to examine the role of anti-Müllerian hormone (AMH) and sex hormones in follicular growth. From April 2016 to March 2019, patients evaluated AMH and basal sex hormones in the Second Hospital of Zhejiang University were involved. The authors discovered that age, follicle-stimulating hormone, and T were factors that most closely associated with AMH level, and T was involved in both DOR and PCOS. Because DOR and PCOS are expressed with insufficient AMH and excessive AMH respectively, total testosterone is suggested to be closely associated with AMH and to play an important role in follicular growth. During the controlled ovarian hyperstimulation process, more attention should be paid to testosterone levels.

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