Role of ALDH1 in the prognosis of esophageal cancer and its relationship with tumor microenvironment
Molecular Carcinogenesis Sep 16, 2017
Chen MF, et al. - This study was carried out to examine the role of aldehyde dehydrogenase 1 (ALDH1) in esophageal squamous cell carcinoma (ESCC). This study suggested the important role of ALDH1 in tumor aggressiveness, and ALDH1 appeared to link with a tumor-promoting microenvironment in esophageal cancer. For the treatment of ESCC, directly targeting ALDH1 or using a COX-2 inhibitor could be a promising strategy.
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