del Mar Álvarez-Torres M, Juan-Albarracín J, Fuster-Garcia E, et al. - In this multicenter retrospective study of 184 glioblastoma persons from seven European centers taking part in the NCT03439332 clinical study, researchers authenticated the correlation between hemodynamic markers from vascular habitats and overall survival in glioblastoma individuals, acknowledging the intercenter variability of acquisition protocols. For glioblastoma individuals in the pretreatment stage the relative cerebral blood volume calculated in high angiogenic tumor, low angiogenic tumor, infiltrated peripheral edema habitats were authenticated as clinically appropriate prognostic biomarkers. This study exhibits the power of the hemodynamic tissue signature habitats to evaluate the glioblastoma vascular heterogeneity and their relations to person prognosis irrespective of intercenter variability.